Dr. Karin Müller

Scientist / Equal opportunity officer

Department of Reproduction Biology

Tel: 0049 (0) 30 5168 - 613

Short curriculum vitae

Karin Müller is a staff scientist in the department Reproduction Biology since 2007. She is interested in the reproduction biology of male gametes as well as in their cryopreservation. In particular, the physiological role of sperm lipids and seminal fluid during sperm transit and fertilization are in focus.
Research interests
  • Characterization of spermatogenesis and sperm function
  • (Cryo)preservation of sperm
  • Analysis of sperm lipid composition and organization of sperm membranes
  • Interactions between sperm, seminal fluid and female genital tract
  • Fluorescence microscopy 
Selected publications

Eder S, Bailey LD, Müller K (2020)

Equilibration in freezing extender alters in vitro sperm–oviduct binding in the domestic cat (Felis catus).

THERIOGENOLOGY 149, 79-87. https://doi.org/10.1016/j.theriogenology.2020.03.017


Bashawat M, Weber A, Müller K (2020)

Cell survival after cryopreservation of dissociated testicular cells from three feline species.

CRYOBIOLOGY doi: 10.1016/j.cryobiol.2020.03.001.


Diemer J, Hahn J, Goldenbogen B, Müller K, Klipp E (2020)

Sperm migration in the genital tract - in silico experiments identify key factors for reproductive success.

bioRxiv https://doi.org/10.1101/2020.03.05.977967.


Svetlichnyy V, Müller P, Pomorski TG, Schulze M, Schiller J, Müller K (2014)

Metabolic incorporation of unsaturated fatty acids into boar spermatozoa lipids and de novo formation of diacylglycerols.

Chem Phys Lipids 177, 41-50. doi: 10.1016/j.chemphyslip.2013.11.001.


Lueders I, Ludwig C, Schröder M, Müller K, Zahmel J, Dehnhard M (2014)

Successful non-surgical artificial insemination and hormonal monitoring in an Asiatic golden cat (Catopuma temmincki). Journal of Zoo and Wildlife Medicine 45(2): 372-379.

doi: http://dx.doi.org/10.1638/2013-0269R.1 URL: http://www.bioone.org/doi/full/10.1638/2013-0269R.1


Pyttel S, Nimptsch A, Böttger J, Zschörnig K, Jakop U, Wegener J, Müller K, Paasch U, Schiller J (2014)

Changes of murine sperm phospholipid composition during epididymal maturation determined by MALDI-TOF mass spectrometry.

Theriogenology 82(3): 396‐402. doi: 10.1016/j.theriogenology.2014.04.017


Müller K, Koster S, Painer J, Söderberg A, Gavier-Widèn D, Brunner E, Dehnhard M, Jewgenow K (2014)

Testosterone production and spermatogenesis in free-ranging Eurasian lynx (Lynx lynx) throughout the year.

Europ J Wildlife Res 60: 569-577 doi: 10.1007/s10344-014-0821-4


Schulze M, C Junkes, P Mueller, S Speck, K Ruediger, M Dathe, K Mueller (2014)

Are cationic antimicrobial peptides an alternative for conventional antibiotics in boar semen preservation? Effects of antimicrobial peptides on liquid-preserved boar spermatozoa.

PLoS ONE 9(6): e100490. doi: 10.1371/journal.pone.0100490


Speck S, Courtiol A, Junkes C, Dathe M, Rüdiger K, Müller K, Schulze M (2014)

Effects of cationic antimicrobial peptides on bacterial contaminants in liquid-preserved semen.

PLoS ONE 9(8): e105949. doi:10.1371/journal.pone.0105949


Braun BC, Müller K, Jewgenow K (2015)

Relaxin family peptides and their receptors during testicular development in the cat.

Domestic Animal Endocrinology 52, 25–34. doi: 10.1016/j.domaniend.2015.01.005


Henry F, Eder S, Reynaud K, Schön J, Wibbelt G, Fontbonne  A, Müller K (2015)

Seminal fluid promotes in vitro sperm-oviduct binding in the domestic cat (Felis catus).

Theriogenology 83, 1373-1380. doi:10.1016/j.theriogenology.2015.01.031.


Schulze M, Grobbel M, Müller K, Junkes C, Dathe M, Rüdiger K, Jung M (2015)

Challenges and limits using antimicrobial peptides in boar semen preservation.

Reprod Dom Anim 50, Suppl 2:5-10. doi: 10.1111/rda.12553 ISSN 0936–6768


Schulze M, Dathe M, Waberski D, Müller K (2016)

Liquid storage of boar semen: current and future perspectives on the use of cationic antimi-crobial peptides to replace antibiotics in semen extenders.

Theriogenology 85, 39-46. doi: 10.1016/j.theriogenology.2015.07.016


Schröter F, Jakop U, Teichmann A, Haralampiev I, TannertA, Wiesner B, Müller P, Müller K (2016)

Lipid Dynamics in Boar Sperm Studied by Advanced Fluorescence Imaging Techniques.

European Biophysics Journal 45(2), 149-163. doi: 10.1007/s00249-015-1084-z. Epub 2015 Oct 19.


Klaus C, Eder S, Franz C, Müller K (2016)

Successful cryopreservation of domestic cat (Felis catus) epididymal sperm after slow equilibration to 15 or 10°C.

Reprod Dom Anim 51, 195–203. doi: 10.1111/rda.12666 ISSN 0936–6768


Tannert A, Otto S, Hoerold J, Jewgenow K, Mueller K (2016)

Ultrasound-assisted cryopreservation of gametes.

IIR International Workshop Cold Applications in Life Sciences, 08.–09.09.2016, Dresden, Germany, ID: 012.

doi: 10.18462/iir.cals.2016.0012


Brütsch SH, Rademacher M, Roth SR, Müller K, Eder S, Viertel D, Franz C, Kühn H, Borchert A (2016)

Male subfertility induced by heterozygous expression of catalytically inactive glutathione

peroxidase 4 is rescued in vivo by systemic inactivation of the Alox15 gene.

J Biol Chem 291(45), 23578-23588. doi: 10.1074/jbc.M116.738930


Luther I, Jakop U, Lueders I, Tordiffe A, Franz C, Schiller J, Kotze A, Müller K (2017)

Semen cryopreservation and radical reduction capacity of seminal fluid in captive African lion (Panthera leo).

Theriogenology 89, 1–10. doi: 10.1016/j.theriogenology.2016.10.024


Schröter F, Müller K, Müller P, Krause E, Braun BC (2017)

Recombinant expression of porcine spermadhesin AWN and its phospholipid interaction: indication for a novel lipid binding property.

Reprod Dom Anim 52(4):585-595. doi: 10.1111/rda.12953. Epub 2017 Mar 21.


Engel KM, Schiller J, Müller K, Dannenberger D, Jakop U (2017)

The phospholipid composition of kangaroo spermatozoa verified by mass spectrometric lipid analysis.

Lipids 52(10):857-869. doi: 10.1007/s11745-017-4283-9.


Sowinska N, Müller K, Niżański W, Jewgenow K (2017)

Mitochondrial distribution, aggregation and activity in oocytes of the domestic cat (Felis catus) after in vitro maturation and vitrification.

Reprod Dom Anim 52(5):806-813. doi: 10.1111/rda.12982.


Braun BC, Okuyama MW, Müller K, Dehnhard M, Jewgenow K (2018)

Steroidogenic enzymes, their products and sex steroid receptors during testis development and spermatogenesis in the domestic cat (Felis catus).

J Steroid Biochem Mol Biol. 178:135-149. doi: 10.1016/j.jsbmb.2017.11.013.


Wegener J, Jakop U, Schiller J, Müller K (2018)

The membrane phospholipid composition of honeybee (Apis mellifera) workers reflects their nutrition, fertility and vitellogenin stores.

Insectes Sociaux 65:381–391. doi:10.1007/s00040-018-0623-x.


Engel KM, Jakop U, Müller K, Grunewald S, Paasch U, Schiller J (2018)

MALDI MS analysis to investigate the lipid composition of sperm.

Current Analytical Chemistry 14:1-12. doi:10.2174/1573411014666181030123256.


Fasel NJ, McMillian K, Jakop U, Méné-Saffrané L, Engel KM, Genoud M, Müller K, Christe P (2018)  

Modification of sperm fatty acid composition during epididymal maturation in bats.

Reproduction     doi:10.1530/REP-18-0463.


Schulze M, Czirják GA, Müller K, Bortfeldt R, Jung M, Jakop U (2019)

Antibacterial defense and sperm quality in boar ejaculates.

Journal of Reproductive Immunology 131:13-20. doi:10.1016/j.jri.2018.11.001.


Fernandez-Gonzalez L, Müller K, Jewgenow K, Zahmel J (2019)

Felid-gamete-rescue within EAZA - efforts and results in biobanking felid oocytes and sperm

Journal of Zoo and Aquarium Research 7(1):41-53.


Jakop U, Svetlichnyy V, Schiller J, Schulze M, Schroeter F, Mueller K (2019)

In vitro supplementation with unsaturated fatty acids improves boar sperm viability after storage at 6 °C.

Animal Reproduction Science 206:60-68. doi.org/10.1016/j.anireprosci.2019.05.008


Bajerski F, Buerger A, Glasmacher B, Keller ERJ, Mueller K, Mühldorfer K, Nagel M, Ruedel H, Müller T, Schenkel J, Overmann J (2020)

Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples.

APPL MICROBIOL BIOTECHNOL 104, 131-144. doi:10.1007/s00253-019-10242-1.


Müller K, Eder S, Jakop U, Schiller J, Müller P, Bashawat M (2019)

Assisted reproduction for felid species conservation – Sperm competences at risk.

Reprod Dom Anim 00:1–6. doi:10.1111/rda.13581


Engel KM, Jakop U, Müller K, Grunewald S, Paasch U, Schiller J (2020)

MALDI MS analysis to investigate the lipid composition of sperm.

Current Analytical Chemistry 16:79-91. doi:10.2174/1573411014666181030123256