PD Dr. Beate Braun

Scientist

Department of Reproduction Biology

 

Tel: 0049 (0) 30 5168 - 616
 
 

Short curriculum vitae

Since 2006 Beate Braun is at the IZW. After being a postdoc for 2 years she was hired for the position of molecular reproduction complementing the department reproduction biology with her biochemical expertise.
 
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Projects
Research interests
  • Molecular and biochemical analysis of hormones and other factors involved in reproduction (e.g. gamete maturation, fertilization and gestation)
  • Functions and physiological adaptations of specific cells and structural units of the reproductive system and their in vitro 2D and 3D culture
  • Recombinant expression of proteins relevant for reproduction and their functional analysis
Selected publications
  1. Braun, B.C., Hryciuk, M.M. & Meneghini, D. Transcriptome analysis of corpora lutea in domestic cats (Felis catus) reveals strong differences in gene expression of various hormones, hormone receptors and regulators across different developmental stages. BMC GENOMICS 26, 325 (2025). https://doi.org/10.1186/s12864-025-11510-3.
  2. Hryciuk MM, Schröter F, Claaßen S, Aurich C, Wauters J, Haße C, Braun BC. (2024): Development of a 3D in vitro model to study corpus luteum of felids based on luteinized cells from antral follicles. CELL TISSUE RES. doi: 10.1007/s00441-024-03937-z.
  3. Bashawat M, Braun BC, Müller K, Hermann BP (2023): Molecular phenotyping of domestic cat (Felis catus) testicular cells across postnatal development - A model for wild felids. Theriogenology Wild. 2023;2:100031. Epub 2023 Apr 20. PMID: 37461433 Free PMC article. doi: 10.1016/j.therwi.2023.100031.
  4. Müller K, Müller P, Lui F, Kroh PD, Braun BC (2023): Porcine spermadhesin AQN-3 binds to negatively charged phospholipids. Chem Phys Lipids. 2023 Aug;254:105306. Epub 2023 May 6. PMID: 37156322. doi: 10.1016/j.chemphyslip.2023.105306.
  5. Hryciuk MM, Schröter F, Hennicke L, Braun BC (2023): Spheroid formation and luteinization of granulosa cells of felids in a long-term 3D culture. Differentiation. 2023 May-Jun;131:38-48. Epub 2023 Apr 6. PMID: 37079952. doi: 10.1016/j.diff.2023.03.002.
  6. Braun BC, Müller K (2023): Role of glyoxalase I and II in somatic and spermatogenic testicular cells during the postnatal development of the domestic cat. Theriogenology. 2023 Feb;197:10-15. Epub 2022 Nov 24. PMID: 36462331. doi: 10.1016/j.theriogenology.2022.11.028.
  7. Kroh PD, Braun BC, Lui F, Müller P, Müller K (2022): Boar spermadhesin AWN: Novel insights in its binding behavior and localization on sperm. BIOL REPROD, doi: 10.1093/biolre/ioab244 Online ahead of print.
  8. Braun BC, Jewgenow K (2022): Role of sex steroids and prostaglandins during the luteal life cycle in domestic cats and lynxes. DOMEST ANIM ENDOCRINOL 78,106689. doi: 10.1016/j.domaniend.2021.106689.
  9. Kehoe S, Jewgenow K, Johnston PR, Braun BC (2022): Early preantral follicles of the domestic cat express gonadotropin and sex steroid signaling potential. BIOL REPROD 106(1), 95-107. doi: 10.1093/biolre/ioab192.
  10. Hryciuk MM, Jewgenow K, Braun BC (2021): Cloprostenol, a synthetic analog of prostaglandin F2α induces functional regression in cultured luteal cells of felids. BIOL REPROD 105(1), 137-147. doi: 10.1093/biolre/ioab070.
  11. Kehoe S, Jewgenow K, Johnston PR, Mbedi S, Braun BC (2021): Signalling pathways and mechanistic cues highlighted by transcriptomic analysis of primordial, primary, and secondary ovarian follicles in domestic cat. SCI REP 11(1), 2683. doi: 10.1038/s41598-021-82051-4. and doi: 10.1038/s41598-021-92241-9.
  12. Hryciuk MM, Jewgenow K, Braun BC (2021): Luteinizing Hormone Effect on Luteal Cells Is Dependent on the Corpus Luteum Stage in Felids. ANIMALS (Basel) 11(1), 179. doi: 10.3390/ani11010179.
  13. Bashawat M, Braun BC, Müller K (2020): Cell survival after cryopreservation of dissociated testicular cells from feline species. CRYOBIOLOGY 97, 191–197. doi:10.1016/j.cryobiol.2020.03.001.
  14. Braun BC, Halaski N, Painer J, Krause E, Jewgenow K (2020): The antioxidative enzyme SOD2 is important for physiological persistence of corpora lutea in lynxes. SCI REP 10, 3681. doi:10.1038/s41598-020-60634-x.
  15. Hecht-Höger AM, Braun BC, Krause E, Meschede A, Krahe R, Voigt CC, Greenwood AD, Czirják GÁ (2020): Plasma proteomic profiles differ between European and North American myotid bats colonized by Pseudogymnoascus destructans. MOL ECOL 29, 1745–1755. doi:10.1111/mec.15437.
  16. Hryciuk MM, Braun BC, Bailey LD, Jewgenow K (2019): Functional and morphological characterization of small and large steroidogenic luteal cells from domestic cats before and during culture. FRONT ENDOCRINOL 10, 724. doi:10.3389/fendo.2019.00724.
  17. Welke RW, Haralampiev I, Schröter F, Braun BC, Herrmann A, Sieben C, Müller P (2019): Inhibition of influenza virus activity by the bovine seminal plasma protein PDC‐109. EUR BIOPHYS J BIOPHYS LETT 48, 503–511. doi:10.1007/s00249-019-01374-3.
  18. Braun BC, Okuyama MW, Müller K, Dehnhard M, Jewgenow K (2018): Steroidogenic enzymes, their products and sex steroid receptors during testis development and spermatogenesis in the domestic cat (Felis catus). J STEROID BIOCHEM MOL BIOL 178, 135–149. doi:10.1016/j.jsbmb.2017.11.013.