Dr. Alexandra Weyrich

Projects
Research interests

- Epigenetic mechanims and regulation of gene expression

- Epigenetics of social systems

- Environmental factors

- Thermoregulation

Selected publications

Westbury MV, Le Duc D, Duchêne DA, Krishnan A, Prost S, Rutschmann S, Grau JH, Dalen L, Weyrich A, Norén K, Werdelin L, Dalerum F, Schöneberg T, Hofreiter M (2021): Ecological specialisation and evolutionary reticulation in extant Hyaenidae. MOL BIOL EVOL msab055. doi:10.1093/molbev/msab055

Li K*, Zhang S*, Song X*, Weyrich A*, Wang Y, Liu X, Wan N, Liu J, Lövy M, Cui H, Frenkel V, Titievsky A, Panov J, Brodsky L, Nevo E (2020): Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation. PROC NATL ACAD SCI USA 117, 32499–32508. *shared first author. doi:10.1073/pnas.2018123117

Weyrich A, Yasar S, Lenz D, Fickel J (2020): Tissue‑specific epigenetic inheritance after paternal heat exposure in male wild guinea pigs. MAMM GENOME 31, 157–169. Invited to special issue. doi:10.1007/s00335-020-09832-6

Guerrero TP, Fickel J, Benhaiem S, Weyrich A (2020): Epigenomics and gene regulation in mammalian social systems. CURR ZOOL 66, 307–319. Invited to special issue on “Social behavior and evolution in the omics era”. doi:10.1093/cz/zoaa005

Weyrich A, Lenz D, Fickel J (2019): Environmental change-dependent transgenerational epigenetic response. GENES 10, 4. Invited to special issue on “Epigenetics and Adaptation”. doi: 10.3390/genes10010004

Weyrich A, Jeschek M, Schrapers KT, Lenz D, Chung H, Rübensam K, Yasar S, Schneemann M, Ortman S, Jewgenow K, Fickel J (2018): Diet changes alter paternally inherited epigenetic pattern in male wild guinea pigs. ENVIRON EPIG 4(2): dvy011. doi:10.1093/eep/dvy011

Weyrich A, Benz S, Karl S, Jeschek M, Jewgenow K, Fickel J (2016): Paternal heat exposure causes DNA methylation and gene expression changes of Stat3 in wild guinea pig sons. ECOL EVOL 6, 2657-2666. doi: 10.1002/ece3.1993

Weyrich A, Lenz D, Jeschek M, Chung TH, Rübensam K, Göritz K, Jewgenow K, Fickel J (2016): Paternal intergenerational epigenetic response to heat exposure in male wild guinea pigs. MOL ECOL 25: 1729-1740. Invited to special issue on “Epigenetic Studies in Ecology and Evolution”. doi:10.1111/mec.13494

Weyrich A, Schüllermann T, Heeger F, Jeschek M, Mazzoni C.J., Chen W, Schumann K, Fickel J (2014): Whole genome sequencing and methylome analysis of the wild guinea pig. BMC GENOMICS 15(1):1036. doi:10.1186/1471-2164-15-1036

Weyrich A, Tang X, Xu G, Schrattenholz A, Hunzinger C, Hennig W (2008): Mammalian DNMTs in the male germ line DNA of Drosophila. BIOCHEM CELL BIOL 86: 380-385. doi:10.1139/O08-096

Last updated on April, 15th 2021.