The Leibniz-IZW is an internationally renowned German research institute. It is part of the Forschungsverbund Berlin e.V. and a member of the Leibniz Association. Our goal is to understand the adaptability of wildlife in the context of global change and to contribute to the enhancement of the survival of viable wildlife populations. For this purpose, we investigate the diversity of life histories, the mechanisms of evolutionary adaptations and their limits, including diseases, as well as the interrelations of wildlife with their environment and people. We use expertise from biology and veterinary medicine in an interdisciplinary approach to conduct fundamental and applied research – from the molecular to the landscape level – in close dialogue with the public and stakeholders. Additionally, we are committed to unique and high-quality services for the scientific community.

+++ Current information on African swine fever: The Leibniz-IZW conducts research on the population dynamics, on models of disease outbreaks in wild boars and on the ecology and human-wildlife interaction in urban areas. African swine fever is a reportable disease in domestic swine and therefor is the purview of the respective federal state laboratories and the Friedrich-Loeffler-Institut (Federal Research Institute for Animal Health) FLI. +++

News

10th oocyte collection in northern white rhino Fatu, conducted by the BioRescue Team in July 2022
10th oocyte collection in northern white rhino Fatu, conducted by the BioRescue Team in July 2022

Advanced assisted reproduction in white rhinos is safe and reliable, shows BioRescue evaluation of 65 OPU-IVF procedures

The BioRescue project develops and pioneers advanced assisted reproduction technologies (aART) for conservation in the face of the imminent extinction of most rhino species and subspecies. In a new scientific analysis published in the journal “Reproduction”, the team evaluated 65 aART procedures comprising hormonal ovarian stimulation, ovum pick-up (OPU), in-vitro oocyte maturation and in-vitro fertilisation (IVF), embryo culture and cryopreservation conducted from 2015 to 2022. The evaluation showed that aART is safe for the donor females with no detrimental health effects, and successful in that it yielded 51 embryos. In fact, regular OPUs benefited the reproductive health of individual female rhinos by improving ovarian function, increasing follicle numbers and instigating the regression of pathological structures such as ovarian cysts.

Read more …

Mosquitoes collected, identified, and tested for viruses by the scientific team (photo: Georg Eibner, Charité)
Mosquitoes collected, identified, and tested for viruses by the scientific team (photo: Georg Eibner, Charité)

Decreasing biodiversity may promote spread of viruses

How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Scientists from Charité – Universitätsmedizin Berlin in cooperation with the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) have now described one piece of that puzzle in the journal “eLife”, showing that the destruction of tropical rainforests harms the diversity of mosquito species. At the same time, more resilient species of mosquitoes become more prevalent – which also means the viruses they carry are more abundant. If there are many individuals of a given species, those viruses can spread quickly.

Read more …

A team from Colossal at a BioRescue procedure at the Ol Pejeta Conservancy in Kenya (photo: Steven Seet)
A team from Colossal at a BioRescue procedure at the Ol Pejeta Conservancy in Kenya (photo: Steven Seet)

Colossal Biosciences joins BioRescue in its mission to save the Northern White Rhino from extinction

With only two living females left, the partnership will contribute to the genetic recovery of the northern white rhino from complete extinction. Colossal developed a pioneering toolkit for the challenging task to restore genetic diversity from museal specimens for a living population of critically endangered species.  

Read more …

Common noctules trapped in urban window in the Ukrain war zone (photo: A. But)
Common noctules trapped in urban window in the Ukrain war zone (photo: A. But)

The Urkrain-war-damaged urban environment in Kharkiv is fatal for bats: Loss of roosts and lethal traps in destroyed buildings

Russia’s war in the Ukraine has severe consequences not only for humans, it also has detrimental effects on populations of urban and semi-urban wildlife in the attacked cities and regions. Scientists from the Ukrainian Bat Rehabilitation Center recently examined the effects of war-related damages to buildings on urban populations of one important and widespread bat species, the Common Noctule (Nyctalus noctula), in the city of Kharkiv in north-eastern Ukraine. They showed that many buildings used by bats as roosts have been destroyed and approximately 7,000 bats were killed. In addition, partially destroyed buildings have become a death trap for bats, resulting in several thousand more victims. The findings are published in the “Journal of Applied Animal Ethics Research”.

 

 

Read more …

BioRescue oocyte collection in Kenya (photo: Jon A. Juarez)
BioRescue oocyte collection in Kenya (photo: Jon A. Juarez)

Five new embryos and new surrogate mothers added to the Northern White Rhino rescue project

Four years since the start of this ambitious project to save the Northern White Rhino from extinction, the BioRescue consortium has made significant progress towards its ultimate aim. Using advanced assisted reproduction technologies, 29 northern white rhino embryos have been created and cryopreserved, ready for a future transfer to a surrogate mother. Most recently, in May 2023, 18 eggs were collected from female Fatu. This resulted in five new embryos created, the highest number of embryos from any collection to date. The sperm for fertilisation came from two different bulls, thereby improving genetic diversity. The BioRescue research project is mainly funded by the German Federal Ministry of Education and Research (BMBF).

Read more …

Domestic boar (Photo: Nicolas Castez - unsplash.com)
Domestic boar (Photo: Nicolas Castez - unsplash.com)

How proteins protect mammalian sperm on their way to the egg cell

The protein AQN-3 from boar sperm binds negatively charged phospholipids

Mammalian seminal fluid contains a variety of proteins secreted by the accessory sex glands that are important for the processes involved in fertilisation. One of these proteins, which is found in ungulates - and in particularly large quantities in boars - is the spermadhesin AQN-3. A science team from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), the Humboldt University of Berlin (HUB) and the Leibniz Institute for Molecular Pharmacology has studied the protein and discovered unexpected properties that could help sperm remain functional until they reach the egg. The findings are published in the scientific journal “Chemistry and Physics of Lipids”.

Read more …

Testis tissue domestic cat (Photo: Bashawat M/Leibniz-IZW)
Testis tissue domestic cat (Photo: Bashawat M/Leibniz-IZW)

Molecular markers identify cell types in the testes of cat species

Berlin, Germany, May 11, 2023. The testis is the natural stem cell reservoir for the formation of male germ cells. Understanding this process is a prerequisite for enabling the formation of male germ cells "in the test tube".

Read more …

Southern white rhino in South Africa (Photo: Nicole Wreyford/unsplash)
Southern white rhino in South Africa (Photo: Nicole Wreyford/unsplash)

African rhinos share retroviruses not found in Asian rhinos or other related species

Rhinoceros belong to a mammalian order called odd-toed ungulates that also include horses and tapirs. They are found in Africa and Asia. Until recently, evidence suggested that throughout their evolutionary history, gammaretroviruses such as Murine leukemia virus had not colonised their genomes, unlike most other mammalian orders. The colonisation process is called retroviral endogenisation and has resulted in most mammalian genomes being comprised of up to ten percent retroviral like sequences.

Read more …