Dr. Karin Müller

Scientist
Department of Reproduction Biology
Short curriculum vitae
- Characterization of spermatogenesis and sperm function
- (Cryo)preservation of sperm
- Analysis of sperm lipid composition and organization of sperm membranes
- Interactions between sperm, seminal fluid and female genital tract
- Fluorescence microscopy
Bajerski F, Bürger A, Glasmacher B, Keller ERJ, Müller K, Mühldorfer K, Nagel M, Rüdel H, Müller T, Schenkel J, Overmann J (2020): Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples. APPL MICROBIOL BIOTECHNOL 104, 131–144. doi:10.1007/s00253-019-10242-1
Bashawat M, Braun BC, Müller K (2020): Cell survival after cryopreservation of dissociated testicular cells from feline species. CRYOBIOLOGY 97, 191–197. doi:10.1016/j.cryobiol.2020.03.001
Diemer J, Hahn J, Goldenbogen B, Müller K, Klipp E (2020): Sperm migration in the genital tract - in silico experiments identify key factors for reproductive success. BIORXIV. doi:10.1101/2020.03.05.977967
Eder S, Bailey LD, Müller K (2020): Equilibration in freezing extender alters in vitro sperm-oviduct binding in the domestic cat (Felis catus). THERIOGENOLOGY 149, 79–87. doi:10.1016/j.theriogenology.2020.03.017
Engel KM, Jakop U, Müller K, Grunewald S, Paasch U, Schiller J (2020): MALDI MS analysis to investigate the lipid composition of sperm. CURRENT ANALYTICAL CHEMISTRY 16, 79-91. doi:10.2174/1573411014666181030123256
Müller K, Eder S, Jakop U, Schiller J, Müller P, Bashawat M (2020): Assisted reproduction for felid species conservation – sperm competences at risk. REPROD DOMEST ANIM 55, 55–60. doi:10.1111/rda.13581
Schulze M, Jakop U, Schröter F, Herrmann C, Leiding C, Müller K, Jung M, Czirják GÁ (2020): Antibacterial defense in bull and boar semen: a putative link to the microbiome and reproductive strategy? THERIOGENOLOGY 157, 335–340. doi:10.1016/j.theriogenology.2020.07.033
Fasel NJ, McMillian K, Jakop U, Mene-Saffrane L, Engel KM, Genoud M, Müller K, Christe P (2019): Modification of sperm fatty acid composition during epididymal maturation in bats. REPRODUCTION 157, 77–85. doi:10.1530/REP-18-0463
Fernandez-Gonzalez L, Müller K, Jewgenow K, Zahmel J (2019): Felid-gamete-rescue within EAZA – efforts and results in biobanking felid oocytes and sperm. J ZOO AQUAR RES 7, 15–24. doi:10.19227/jzar.v7i1.369
Jakop U, Svetlichnyy V, Schiller J, Schulze M, Schroeter F, Müller K (2019): In vitro supplementation with unsaturated fatty acids improves boar sperm viability after storage at 6 °C. ANIM REPROD SCI 206, 60–68. doi:10.1016/j.anireprosci.2019.05.008
Schulze M, Czirják GÁ, Müller K, Bortfeldt R, Jung M, Jakop U (2019): Antibacterial defense and sperm quality in boar ejaculates. J REPROD IMMUNOL 131, 13–20. doi:10.1016/j.jri.2018.11.001
Braun BC, Okuyama MW, Müller K, Dehnhard M, Jewgenow K (2018): Steroidogenic enzymes, their products and sex steroid receptors during testis development and spermatogenesis in the domestic cat (Felis catus). J STEROID BIOCHEM MOL BIOL 178, 135–149. doi:10.1016/j.jsbmb.2017.11.013
Wegener J, Jakop U, Schiller J, Müller K (2018): The membrane phospholipid composition of honeybee (Apis mellifera) workers reflects their nutrition, fertility and vitellogenin stores. INSECT SOC 65, 381–391. doi:10.1007/s00040-018-0623-x
Engel KM, Schiller J, Müller K, Dannenberger D, Jakop U (2017): The phospholipid composition of kangaroo spermatozoa verified by mass spectrometric lipid analysis. LIPIDS 52, 857–869. doi:10.1007/s11745-017-4283-9
Luther I, Jakop U, Lueders I, Tordiffe A, Franz C, Schiller J, Kotze A, Müller K (2017): Semen cryopreservation and radical reduction capacity of seminal fluid in captive African lion (Panthera leo). THERIOGENOLOGY 89, 295–304. doi:10.1016/j.theriogenology.2016.10.024
Schröter F, Müller K, Müller P, Krause E, Braun BC (2017): Recombinant expression of porcine spermadhesin AWN and its phospholipid interaction: indication for a novel lipid binding property. REPROD DOMEST ANIM 52, 585–595. doi:10.1111/rda.12953
Sowinska N, Müller K, Niżański W, Jewgenow K (2017): Mitochondrial characteristics in oocytes of the domestic cat (Felis catus) after in vitro maturation and vitrification. REPROD DOMEST ANIM 52, 806–813. doi:10.1111/rda.12982
Brütsch SH, Rademacher M, Roth SR, Müller K, Eder S, Viertel D, Franz C, Kühn H, Borchert A (2016): Male subfertility induced by heterozygous expression of catalytically inactive glutathione peroxidase 4 is rescued in vivo by systemic inactivation of the Alox15 gene. J BIOL CHEM 291, 23578–23588. doi:10.1074/jbc.M116.738930
Klaus C, Eder S, Franz C, Müller K (2016): Successful cryopreservation of domestic cat (Felis catus) epididymal sperm after slow equilibration to 15 or 10°C. REPROD DOMEST ANIM 51, 195–203. doi:10.1111/rda.12666
Schröter F, Jakop U, Teichmann A, Haralampiev I, Tannert A, Wiesner B, Müller P, Müller K (2016): Lipid dynamics in boar sperm studied by advanced fluorescence imaging techniques. EUR BIOPHYS J BIOPHYS LETT 45, 149–163. doi:10.1007/s00249-015-1084-z
Schulze M, Dathe M, Waberski D, Müller K (2016): Liquid storage of boar semen: Current and future perspectives on the use of cationic antimicrobial peptides to replace antibiotics in semen extenders. THERIOGENOLOGY 85, 39–46. doi:10.1016/j.theriogenology.2015.07.016
Tannert A, Otto S, Hoerold J, Jewgenow K, Mueller K (2016): Ultrasound-assisted cryopreservation of gametes. IIR International Workshop Cold Applications in Life Sciences, 08.–09.09.2016, Dresden, Germany, ID: 012. doi: 10.18462/iir.cals.2016.0012
Braun BC, Müller K, Jewgenow K (2015): Expression profiles of relaxin family peptides and their receptors indicate their influence on spermatogenesis in the domestic cat (Felis catus). DOMEST ANIM ENDOCRINOL 52, 25–34. doi:10.1016/j.domaniend.2015.01.005
Henry F, Eder S, Reynaud K, Schön J, Wibbelt G, Fontbonne A, Müller K (2015): Seminal fluid promotes in vitro sperm-oviduct binding in the domestic cat (Felis catus). THERIOGENOLOGY 83, 1373–1380. doi:10.1016/j.theriogenology.2015.01.031
Schulze M, Grobbel M, Müller K, Junkes C, Dathe M, Rüdiger K, Jung M (2015): Challenges and limits using antimicrobial peptides in boar semen preservation. REPROD DOMEST ANIM 50, Suppl 2:5-10. doi:10.1111/rda.12553
Lüders I, Ludwig C, Schröder M, Müller K, Zahmel J, Dehnhard M (2014): Successful non-surgical artificial insemination and hormonal monitoring in an Asiatic golden cat (Catopuma temmincki). J ZOO WILDL MED 45, 372–379. doi:10.1638/2013-0269r.1
Müller K, Koster S, Painer J, Söderberg A, Gavier-Widèn D, Dehnhard M, Jewgenow K (2014): Testosterone production and spermatogenesis in free-ranging Eurasian lynx (Lynx lynx) throughout the year. EUR J WILDL RES 60, 569–577. doi:10.1007/s10344-014-0821-4
Pyttel S, Nimptsch A, Böttger J, Zschörnig K, Jakop U, Wegener J, Müller K, Paasch U, Schiller J (2014): Changes of murine sperm phospholipid composition during epididymal maturation determined by MALDI-TOF mass spectrometry. THERIOGENOLOGY 82, 396–402. doi:10.1016/j.theriogenology.2014.04.017
Schulze M, Junkes C, Müller P, Speck S, Rüdiger K, Dathe M, Müller K (2014): Are cationic antimicrobial peptides an alternative for conventional antibiotics in boar semen preservation? Effects of antimicrobial peptides on liquid-preserved boar spermatozoa. PLOS ONE 9, e100490. doi:10.1371/journal.pone.0100490
Speck S, Courtiol A, Junkes C, Dathe M, Müller K, Schulze M (2014): Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen. PLOS ONE 9, e105949. doi:10.1371/journal.pone.0105949
Svetlichnyy V, Müller P, Pomorski TG, Schulze M, Schiller J, Müller K (2014): Metabolic incorporation of unsaturated fatty acids into boar spermatozoa lipids and de novo formation of diacylglycerols. CHEM PHYS LIPIDS 177, 41–50. doi:10.1016/j.chemphyslip.2013.11.001
Nimptsch A, Fuchs B, Süß R, Zschörnig K, Jakop U, Göritz F, Schiller J, Müller K (2013): A simple method to identify ether lipids in spermatozoa samples by MALDI-TOF mass spectrometry. ANAL BIOANAL CHEM 405, 6675–6682. doi:10.1007/s00216-013-7147-z
Schulze M, Ruediger K, Müller K, Jung M, Well C, Reissmann M (2013): Development of an in vitro index to characterize fertilizing capacity of boar ejaculates. ANIM REPROD SCI 140, 70–76. doi:10.1016/j.anireprosci.2013.05.012
Simon P, Bäumner S, Busch O, Röhrich R, Kaese M, Richterich P, Wehrend A, Müller K, Gerardy-Schahn R, Mühlenhoff M, Geyer H, Geyer R, Middendorff R, Galuska SP (2013): Polysialic acid is present in mammalian semen as a post-translational modification of NCAM and the polysialyltransferase ST8SiaII. J BIOL CHEM 228, 18825–18833. doi:10.1074/jbc.M113.451112
Wegener J, Bresler K, Teuber K, Fuchs B, Schiller J, Müller K (2013): Conservation of honey bee (Apis mellifera) sperm phospholipids during storage in the bee queen – a TLC/MALDI-TOF MS Study. EXP GERONTOL 48, 213–222. doi:10.1016/j.exger.2012.12.009