Prof. Dr. Jennifer Schön

Abteilungsleiterin

Abteilung für Reproduktionsbiologie

 

Tel: 0049 (0) 30 5168 - 611
 
 

Kurzer Lebenslauf

  • 2022-heute: Professorin an der Technischen Universität Berlin, Institut für Biotechnologie
  • 2021-heute: Leiterin der Abt. Reproduktionsbiologie, Leibniz-IZW
  • 2014-2021: Leiterin der Abteilung Reproduktionszellbiologie, FBN Dummerstorf
  • 2013-2014: Wissenschaftliche Mitarbeiterin der Berlin-Brandenburg School for Regenerative Therapies, Charité Berlin
  • 2004-2012: Wissenschaftliche Mitarbeiterin am Institut für Veterinär-Biochemie, FU Berlin
  • 2004: Promotion (Dr. med. vet.), Freie Universität Berlin und Leibniz-IZW
Projekte

Funktionelle Biodiversität von Zellen des Reproduktionssystems

Signaturen männlicher/ weiblicher Fruchtbarkeit

Wildtierendokrinologie

Biobanking als Grundlage für assistierte Reproduktionstechniken

Reproduktionsbiologie von Luchsen - Grundlagen für die Erhaltungszucht des Iberischen Luches

Dialogue(s) for fertility: deciphering spermatozoa-oviduct interactions and their implications for artificial insemination in cattle

Fertility impairment by maternal stress:

Using a novel 3D in vitro system to decipher the impact of cortisol on oviduct epithelium physiology, oviduct-derived extracellular vesicles and early embryonic development

Forschungsinteressen
  • Physiologie des weiblichen Reproduktionstraktes
  • Interaktionen von Gameten und Embryonen mit dem maternalen Reproduktionstrakt
  • Einfluss von Stress auf die frühe Trächtigkeit
Ausgewählte Publikationen
  1. Reyer H, Abou‐Soliman I, Schulze M, Henne H, Reinsch N, Schoen J, Wimmers K (2024): Genome‐Wide Association Analysis of Semen Characteristics in Piétrain Boars. GENES 15, 382. doi:10.3390/genes15030382.
  2. Du S, Trakooljul N, Palma‐Vera SE, Murani E, Schuler G, Schoen J, Chen S (2023): Regulation of porcine oviduct epithelium functions via progesterone and estradiol is influenced by cortisol. ENDOCRINOLOGY 164, bqac176. doi:10.1210/endocr/bqac176.
  3. Ghasemian K, Broer I, Schoen J, Killisch R, Kolp N, Springer A, Huckauf J (2023): Oral and subcutaneous immunization with a plant‐produced mouse‐specific zona pellucida 3 peptide presented on hepatitis B core antigen virus‐like particles. VACCINES 11, 462. doi:10.3390/vaccines11020462.
  4. Ghasemian K, Broer I, Schoen J, Kolp N, Killisch R, Huckauf J (2023): Plant‐produced mouse‐specific zona pellucida 3 peptide induces immune responses in mice. VACCINES 11, 153. doi:10.3390/vaccines11010153.
  5. Ghasemian K, Broer I, Schoen J, Kolp N, Killisch R, Mikkat S, Huckauf J (2023): Immunogenicity and contraceptive efficacy of plant‐produced putative mouse‐specific contraceptive peptides. FRONT PLANT SCI 14, 1191640. doi:10.3389/fpls.2023.1191640.
  6. Mahé C, Lavigne R, Com E, Pineau C, Zlotkowska AM, Tsikis G, Mermillod P, Schoen J, Saint‐Dizier M (2023): The sperm‐interacting proteome in the bovine isthmus and ampulla during the periovulatory period. J ANIM SCI BIOTECHNOL 14, 30. doi:10.1186/s40104-022-00811-2.
  7. Mahé C, Pranomphon T, Reynaud K, Laffont L, Meylheuc T, Schoen J, Mermillod P, Saint‐Dizier M (2023): Sperm‐fluid‐cell interplays in the bovine oviduct: glycosaminoglycans modulate sperm binding to the isthmic reservoir. SCI REP 13, 10311. doi:10.1038/s41598-023-37469-3.
  8. Eder S, Müller K, Chen S, Schoen J (2022): Long‐term culture of feline oviduct epithelial cells on permeable filter supports. CYTOTECHNOLOGY 74, 531–538. doi:10.1007/s10616-022-00542-2.
  9. Mahé C, Lavigne R, Com E, Pineau C, Locatelli Y, Zlotkowska AM, Almiñana C, Tsikis G, Mermillod P, Schoen J, Saint‐Dizier M (2022): Spatiotemporal profiling of the bovine oviduct fluid proteome around the time of ovulation. SCI REP 12, 4135. doi:10.1038/s41598-022-07929-3.
  10. Müller‐Eigner A, Sanz‐Moreno A, de‐Diego I, Venkatasubramani AV, Langhammer M, Gerlini R, Rathkolb B, Aguilar‐Pimentel A, Klein‐Rodewald T, Calzada‐Wack J, Becker L, Palma‐Vera S, Gille B, Forne I, Imhof A, Meng C, Ludwig C, Koch F, Heiker JT, Kuhla A, Caton V, Brenmoehl J, Reyer H, Schoen J, Fuchs H, Gailus‐Durner V, Hoeflich A, de Angelis MH, Peleg S (2022): Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse. COMMUN BIOL 5, 408. doi:10.1038/s42003-022-03339-3.
  11. Palma-Vera SE, Reyer H, Langhammer M, Reinsch N, Derezanin L, Fickel J, Qanbari S, Weitzel JM, Franzenburg S, Hemmrich-Stanisak G, Schoen J. Genomic characterization of the world's longest selection experiment in mouse reveals the complexity of polygenic traits. BMC Biol. 2022, 21;20(1):52. http://dx.doi.org/10.1186/s12915-022-01248-9.
  12. Schmidhauser M, Ulbrich SE, Schoen J (2022): Luminal and glandular epithelial cells from the porcine endometrium maintain cell type‐specific marker gene expression in air‐liquid interface culture. STEM CELL REV REP 18, 2928–2938. doi:10.1007/s12015-022-10410-3.
  13. Schulze M, Mohammadpour F, Schröter F, Jakop U, Hönicke H, Hasenfuss T, Henne H, Schoen J, Müller K(2021): Suitability of semen stress tests for predicting fertilizing capacity of boar ejaculates. THERIOGENOLOGY 176, 73–81. doi:10.1016/j.theriogenology.2021.09.024.
  14. Chen S. and Schoen J. Using the Air-Liquid Interface Approach to Foster Apical-Basal Polarization of Mammalian Female Reproductive Tract Epithelia In Vitro. Methods Mol Biol. 2021, 2273:251-262.http://dx.doi.org/10.1007/978-1-0716-1246-0_18.
  15. Du, S.Z., N. Trakooljul, Schoen and S. Chen. Does Maternal Stress Affect the Early Embryonic Microenvironment? Impact of Long-Term Cortisol Stimulation on the Oviduct Epithelium. Int. J. Mol. Sci. 2020, 21(2), 443;http://dx.doi.org/10.3390/ijms21020443.
  16. Chen, S., S. E. Palma-Vera, B. Kempisty, M. Rucinski, A. Vernunft, and Schoen. In Vitro Mimicking of Estrous Cycle Stages: Dissecting the Impact of Estradiol and Progesterone on Oviduct Epithelium. Endocrinology 2018,159(9):3421-3432http://dx.doi.org/10.1210/en.2018-00567.
  17. Chen, S., S. E. Palma-Vera, M. Langhammer, S. P. Galuska, B. C. Braun, E. Krause, A. Lucas-Hahn, and Schoen. 2017. An air-liquid interphase approach for modeling the early embryo-maternal contact zone. Scientific reports 7:42298. http://dx.doi.org/10.1038/srep42298.
  18. Chen, S., R. Einspanier, and Schoen. 2015. Transepithelial electrical resistance (TEER): a functional parameter to monitor the quality of oviduct epithelial cells cultured on filter supports. Histochemistry and cell biology 144(5):509-515.http://dx.doi.org/10.1007/s00418-015-1351-1.
  19. Chen, S., R. Einspanier, and Schoen. 2013a. In vitro mimicking of estrous cycle stages in porcine oviduct epithelium cells: estradiol and progesterone regulate differentiation, gene expression, and cellular function. Biology of reproduction 89(3):54.http://dx.doi.org/10.1095/biolreprod.113.108829.
  20. Chen, S., R. Einspanier, and Schoen. 2013b. Long-term culture of primary porcine oviduct epithelial cells: validation of a comprehensive in vitro model for reproductive science. Theriogenology 80(8):862-869.http://dx.doi.org/10.1016/j.theriogenology.2013.07.011.